NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Siriwardena A N, Qureshi M Z, Dyas J V et al. Magic Bullets for insomnia? Patients’ use and experiences of newer (Z drugs) versus older (benzodiazepine) hypnotics for sleep […]
Category Archives: CNS and mental health
NPC Archive Item: Short-term serious adverse effects of antipsychotics in people with dementia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Rochon PA, Normand S-L, Gomes T, et al. Antipsychotic therapy and short-term serious events in older adults with dementia. Arch Intern Med. 2008;168:1090–6 Even short-term prescribing of […]
NPC Archive Item: Modified-release melatonin launched for short-term treatment of primary insomnia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Wade AG, Ford I, Crawford G, et al. Efficacy of prolonged release melatonin in insomnia patients aged 55–80 years: quality of sleep and next-day alertness outcomes. Curr Med Res […]
NPC Archive Item: Medicines Management Self Assessment Toolkit – Mental Health
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The toolkit, which was introduced in April and prepared by the National Institute for Mental Health in England (NIMHE), is designed to help Mental Health Trusts (MHTs) to review […]
NPC Archive Item: Newer antidepressants produce clinically significant benefits over placebo only in the severely depressed
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Kirsch I, et al. Initial severity and antidepressant benefits: A meta-analysis of data submitted to the Food and Drug Administration. PLoS Med 2008 5(2): 45. doi:10.1371/journal.pmed.0050045 What is the […]
NPC Archive Item: NPC Podcast – 26th February 2008
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Antidepressants – Questions around benefits in non-severe depression / evidence of publication bias [podcast]http://www.npc.nhs.uk/podcast/NPCiPodcast_26thFeb08.mp3[/podcast] Subscribe to the NPC podcast via the iTunes store Subscribe to the NPC podcast via […]
NPC Archive Item: Publication bias in studies of antidepressants?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Turner EH, et al, Selective publication of antidepressant trials and its influence on apparent efficacy. New Engl J Med 2008;358:252-260 What is the background to this? It is important […]
NPC Archive Item: Aripiprazole versus conventional (typical) antipsychotics for schizophrenia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Bhattacharjee J, El-Sayeh HGG. Aripiprazole versus typicals for schizophrenia. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No.: CD006617. DOI: 10.1002/14651858.CD006617.pub2 What is the background to this? – […]
NPC Archive Item: Varenicline▼ compared with nicotine replacement therapy for smoking cessation
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Stapleton JA, et al. Varenicline in the routine treatment of tobacco dependence: a pre-post comparison with nicotine replacement therapy and an evaluation in those with mental illness. Addiction 2008;103:146-54. […]
NPC Archive Item: Cholinesterase inhibitors don’t help in mild cognitive impairment
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Raschetti R, et al. Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials. PLoS Medicine 2007; 4(11): e338. doi:10.1371/journal.pmed.0040338 What is the background to this? Dementia […]