Category Archives: CNS and mental health

NPC Archive Item: No difference in effectiveness of ‘second-generation’ antidepressants

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. A recent systematic review concludes that current evidence does not support the choice of one second-generation antidepressant (e.g. SSRIs, venlafaxine, duloxetine▼, mirtazapine) over another on the basis of efficacy […]

NPC Archive Item: Olanzapine long-acting injection for schizophrenia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. EMEA Summary of Positive Opinion for olanzapine long-acting injection (Zypadhera ®) In September 2008, the Committee for Medicinal Products for Human Use (CHMP) recommended European licensing approval of olanzapine […]

NPC Archive Item: Concomitant use of an SSRI and NSAID increases the risk of an upper GI bleed six times

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Loke YK, Trivedi AN, Singh S. Meta-analysis: gastrointestinal bleeding due to interaction between selective serotonin reuptake inhibitors and non-steroidal anti-inflammatory drugs. Aliment Pharmacol Ther 2008;27:31–40 The relative risk of […]

NPC Archive Item: More evidence that antipsychotics increase stroke risk

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ 2008;337:a1227 A recent study adds to evidence that typical and atypical antipsychotics are […]

NPC Archive Item: NICE issues guidance on ADHD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. NICE Guidance on attention deficit hyperactivity disorder. Clinical Guideline No.72. September 2008 NICE has issued guidance on the diagnosis and management of attention deficit hyperactivity disorder (ADHD) in children […]

NPC Archive Item: National Dementia Strategy to consider antipsychotic use

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. A Department of Health review is being conducted as part of the National Dementia Strategy to investigate and suggest actions to reduce the inappropriate prescribing of antipsychotics to people […]

NPC Archive Item: Patients’ experience and perception of using hypnotics.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Siriwardena A N, Qureshi M Z, Dyas J V et al. Magic Bullets for insomnia? Patients’ use and experiences of newer (Z drugs) versus older (benzodiazepine) hypnotics for sleep […]