NPC Archive Item: Antipsychotic use and life expectancy of people with schizophrenia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30th July 2009 An observational study in Finland confirms the large gap in life expectancy between people with schizophrenia and the general population.  However, it also suggests that long-term […]

NPC Archive Item: June Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 11th June 2009 The MHRA and CHM have published the June edition of Drug Safety Update. This issue gives […]

NPC Archive Item: Cholinesterase inhibitors associated with syncope in patients with dementia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18th May 2009 An observational study has found that cholinesterase inhibitors (donepezil, galantamine and rivastigmine▼) are associated with increased rates of syncope, bradycardia, permanent pacemaker insertion and hip fracture […]

NPC Archive Item: NICE updates schizophrenia guideline

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd April 2009 NICE has updated its clinical guideline on the management of schizophrenia. With regard to choice of antipsychotic, NICE does not recommend use of any particular drug […]

NPC Archive Item: Antipsychotics increase mortality in patients with Alzheimer’s disease

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Extended follow-up of the DART-AD trial found patients with Alzheimer’s disease who continued antipsychotic medication for behavioural or psychiatric problems were twice as likely to die as those switched […]