NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30th July 2009 An observational study in Finland confirms the large gap in life expectancy between people with schizophrenia and the general population. However, it also suggests that long-term […]
Category Archives: CNS and mental health
NPC Archive Item: Getting the Medicines Right: Medicines Management in Adult and Older Adult Acute Mental Health Wards.
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 28th July 2009 Introduction In July 2009 the document ‘Getting the Medicines Right: Medicines Management in Adult and Older Adult Acute Mental Health Wards’ was published to support the […]
NPC Archive Item: June Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 11th June 2009 The MHRA and CHM have published the June edition of Drug Safety Update. This issue gives […]
NPC Archive Item: Cholinesterase inhibitors associated with syncope in patients with dementia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18th May 2009 An observational study has found that cholinesterase inhibitors (donepezil, galantamine and rivastigmine▼) are associated with increased rates of syncope, bradycardia, permanent pacemaker insertion and hip fracture […]
NPC Archive Item: NICE updates schizophrenia guideline
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd April 2009 NICE has updated its clinical guideline on the management of schizophrenia. With regard to choice of antipsychotic, NICE does not recommend use of any particular drug […]
NPC Archive Item: Evidence to support sertraline as first-line drug treatment option for major depression
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25th February 2009 A meta-analysis which considered the comparative efficacy of 12 second-generation antidepressants, has concluded that sertraline may be the best choice when starting treatment for moderate to […]
NPC Archive Item: Atypical and typical antipsychotics may double the risk of sudden cardiac death
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 5th February 2009 An observational study from Tennessee suggests that typical and atypical antipsychotic drugs approximately double the risk of sudden cardiac death. The absolute increase is approximately an […]
NPC Archive Item: EMEA recommendations for safer use of methylphenidate-containing medicines
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4th February 2009 The EMEA’s Committee for Medicinal Products for Human Use (CHMP) has reviewed methylphenidate due to concerns over cardiovascular and cerebrovascular risks. They also considered the risk […]
NPC Archive Item: New evidence to support individualised antipsychotic drug treatment in patients with schizophrenia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. A recent meta-analysis concludes that all antipsychotic drugs differ in their efficacy and adverse effects and they are not a homogeneous group. This supports an individualised approach to treatment, […]
NPC Archive Item: Antipsychotics increase mortality in patients with Alzheimer’s disease
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Extended follow-up of the DART-AD trial found patients with Alzheimer’s disease who continued antipsychotic medication for behavioural or psychiatric problems were twice as likely to die as those switched […]