NPC Archive Item: Cholinesterase inhibitors associated with syncope in patients with dementia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18th May 2009 An observational study has found that cholinesterase inhibitors (donepezil, galantamine and rivastigmine▼) are associated with increased rates of syncope, bradycardia, permanent pacemaker insertion and hip fracture […]

NPC Archive Item: NICE updates schizophrenia guideline

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd April 2009 NICE has updated its clinical guideline on the management of schizophrenia. With regard to choice of antipsychotic, NICE does not recommend use of any particular drug […]

NPC Archive Item: Antipsychotics increase mortality in patients with Alzheimer’s disease

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Extended follow-up of the DART-AD trial found patients with Alzheimer’s disease who continued antipsychotic medication for behavioural or psychiatric problems were twice as likely to die as those switched […]

NPC Archive Item: Z-drugs increase the risk of road traffic accidents

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. A study in Norway has found that prescription of Z-drugs is associated with around a doubled increased relative risk of road traffic accidents compared to those who don’t take […]