Rapid Update 2 – October 2019: Public health assessment finds a quarter of adults in England prescribed medicines associated with dependence or withdrawal

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Rapid Update 3 – July 2019: Pain: Tramadol for osteoarthritis – systematic review finds little benefit and increased adverse events compared with placebo

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Rapid Update 1- June 2018: Opioids: interventions to reduce use in chronic non-cancer pain

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Rapid Update 2- December 2017: Gabapentin and opioids: Observational study finds increased risk of opioid-related death when used in combination

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Rapid Update 3- September 2017: Osteoarthritis: systematic review and individual patient data meta-analysis finds no good evidence to support the use of glucosamine

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Rapid Update 2- June 2017: NSAIDs and risk of acute myocardial infarction

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Rapid Update 1 – April 2017: Pain: meta-analysis finds limited efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) for spinal pain

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