Rapid Update 3 – July 2019: Pain: Tramadol for osteoarthritis – systematic review finds little benefit and increased adverse events compared with placebo

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Rapid Update 1- June 2018: Opioids: interventions to reduce use in chronic non-cancer pain

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Rapid Update 2- December 2017: Gabapentin and opioids: Observational study finds increased risk of opioid-related death when used in combination

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Rapid Update 3- September 2017: Osteoarthritis: systematic review and individual patient data meta-analysis finds no good evidence to support the use of glucosamine

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Rapid Update 2- June 2017: NSAIDs and risk of acute myocardial infarction

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Rapid Update 1 – April 2017: Pain: meta-analysis finds limited efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) for spinal pain

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Rapid Update 3 – December 2016: Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis

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Network meta-analysis finds significant differences between types of placebo and improvements in pain score (Nov-15)

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NPC Archive Item: Even more data on cardiovascular risks of NSAIDs: time to review prescribing

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10 October 2011 A meta-analysis of observational studies has added to the evidence base confirming an increased risk of cardiovascular (CV) events with coxibs and traditional NSAIDs. The study […]

NPC Archive Item: Scottish Medicines Consortium accepts restricted use of tapentadol▼ prolonged-release tablets for severe chronic pain in adults

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 02 September 2011 After a re-submission by the manufacturer, the Scottish Medicines Consortium (SMC) has accepted tapentadol▼ prolonged-release (Palexia® SR) tablets for restricted use within NHS Scotland, for the […]