Rapid Update 1 – February 2019 Hormone replacement therapy (HRT): Further evidence that oral but not transdermal HRT is associated with venous thromboembolism

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Rapid Update 2 – January 2019 Influenza: Large cohort study finds influenza vaccine decreases risk of death in people with heart failure

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Rapid Update 2- March 2018: Communication and shared decision-making: UK questionnaire-based study finds that many people do not fully understand common medical terms

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Rapid Update 4 – October 2016: Statins: Review and interpretation of the evidence for efficacy and safety

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NPC Archive Item: Oseltamivir and complications of influenza: updated Cochrane review

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 February 2012 An updated Cochrane review has found that although oseltamivir effectively reduced the duration of seasonal influenza symptoms by about a day, it did not reduce the […]

NPC Archive Item: Coping with information overload

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 August 2011 An editorial in the BMJ highlighted the difficulties of coping with information overload in medicine and outlined various strategies that doctors use to deal with the […]

NPC Archive Item: Diagnostic error: more about problems in thinking than problems with knowing

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 28 July 2011 In a retrospective audit, published in 2005, 100 cases of diagnostic errors were used to determine the significance of the roles that cognitive and system-related factors […]

NPC Archive Item: Reboxetine — a striking example of publication bias

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 1 November 2010 A meta-analysis of published and unpublished data on reboxetine for the acute treatment of major depression found it, overall, to be an ineffective and potentially harmful antidepressant. […]

NPC Archive Item: Association found between financial conflicts of interest and authors’ views on MI risk with rosiglitazone

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19th July 2010 A systematic review found that there was a link between financial conflicts of interests with pharmaceutical companies and the orientation of views expressed by authors on […]

NPC Archive Item: CV risk reduction in diabetes: law of cumulative benefits, diminishing returns

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15th July 2010 This modelling study demonstrates the “law of cumulative benefits” or conversely a “law of diminishing returns” with regard to the intensification of BP-lowering and lipid-modification therapy […]