Rapid Update 1- August 2017: Alzheimer’s disease: increased risk of pneumonia observed in people treated with benzodiazepines

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Rapid Update 2 – November 2016: Dementia: No reduction in antipsychotic prescribing in care homes 4 years after introduction of the National Dementia Strategy

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Bipolar disorder: prevalence of unrecognised bipolar disorder in patients prescribed antidepressants in UK primary care (Mar-16)

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Study suggests psychotropic drugs may be overprescribed for people with intellectual disability (Oct-15)

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Intracranial haemorrhage: risk increased with concurrent use of antidepressants and non-steroidal anti-inflammatory drugs (Sep-15)

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Antipsychotics: more data on the risk of death in people with dementia (May-15)

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NPC Archive Item: Continuing donepezil treatment in patients with moderate-to-severe Alzheimer’s disease

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 20th March 2012 In a relatively small (n=295) randomised controlled trial of moderate-to-severe Alzheimer’s disease, continuing donepezil resulted in slower cognitive decline over 12 months than stopping donepezil. However, […]

NPC Archive Item: A comparison of the effectiveness of antimanic drugs in acute mania

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 November 2011 A systematic review and multiple-treatment meta-analysis suggests that antipsychotic drugs are significantly more effective than mood stabilisers in the acute treatment of manic episodes in adults. […]

NPC Archive Item: Scottish Medicines Consortium accepts use of paliperidone palmitate▼ injection for schizophrenia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 14 November 2011 Following a re-submission by the manufacturer, the Scottish Medicines Consortium (SMC) has accepted paliperidone palmitate▼ prolonged-release injection for use within NHS Scotland for specific adult patients* […]

NPC Archive Item: Treating pain to reduce behavioural disturbances in people with dementia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 August 2011 A randomised controlled trial suggests that a systematic approach to the management of pain in people with dementia reduces agitation and may reduce the number of […]