NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 March 2010 A US cohort study in patients with COPD found an increased risk of CV events associated with the use of ipratropium within the past six months. […]
Category Archives: Respiratory
NPC Archive Item: Drug Safety Update from MHRA/CHM (February 2010)
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 19 February 2010 The MHRA and CHM have published the February edition of Drug Safety Update This edition includes […]
NPC Archive Item: Cochrane review does not support ICS plus LABA in steroid naïve patients with persistent asthma
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 12 January 2010 A Cochrane review found that current evidence does not support the use of combination therapy with ICS plus LABA as first choice preventer therapy in adults […]
NPC Archive Item: Observational data in swine influenza pandemic indicate benefit of early antivirals; new Cochrane review finds oseltamivir▼’s ability to prevent complications of seasonal influenza in otherwise healthy adults not proven.
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22 December 2009 Action Health professionals’ responses to the swine influenza pandemic should not be affected by the controversy regarding oseltamivir▼’s ability to prevent complications of seasonal influenza in […]
NPC Archive Item: Roflumilast in COPD
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18 November 2009, Two one-year RCTs (AURA and HERMES) showed that roflumilast modestly improved lung function in patients with severe COPD who were symptomatic and not using an inhaled […]
NPC Archive Item: Triple versus single therapy in COPD
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4 November 2009 A short-term randomised controlled trial claims benefits for the addition of inhaled budesonide/formoterol to tiotropium (i.e. triple vs. single therapy) in patients with COPD. However, limitations […]
NPC Archive Item: Wash your hands (and more): physical barriers help stop viral infections spreading
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27 October 2009 This updated Cochrane review found that, although the evidence is of limited quality, hygiene and physical barriers can be effective in reducing or preventing the spread […]
NPC Archive Item: Combined LABA/ICS may not offer clinically important benefits over LABA alone in COPD, but is associated with serious adverse effects
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27 October 2009 A large systematic review found that compared with LABA monotherapy, combined LABA/ICS did not statistically significantly reduce severe exacerbations, all-cause mortality, respiratory mortality or CV mortality, […]
NPC Archive Item: New BTS guidance on management of community acquired pneumonia (CAP)
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 14 October 2009 The British Thoracic Society (BTS) has published updated guidance on management of community acquired pneumonia (CAP) in adults. This updates the 2004 guidance. What’s new in […]
NPC Archive Item: Meta-analysis suggests budesonide does not increase pneumonia risk in COPD patients
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd October 2009 This meta-analysis of individual patient data found that budesonide treatment for 12-months does not increase the risk of pneumonia in people with COPD. However, other studies […]