NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 31 May 2011 A pragmatic randomised study found that a leukotriene receptor antagonist (LTRA) was equivalent to an inhaled corticosteroid (ICS) as first-line preventer therapy, and to a long-acting […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Date amended 20 May 2011 Date originally posted 28 April 2011 The POET-COPD randomised controlled trial found that tiotropium reduced the risk of moderate or severe exacerbations, compared with […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 14th March 2011 A randomised controlled trial (RCT) suggests that inhaled corticosteroids (ICS) plus salbutamol as reliever therapy might be an effective step-down strategy for children (>5years of age) with […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 8th February 2011 A Canadian cohort study identified that patients treated for respiratory disease using inhaled corticosteroids (ICS) over a period of 5.5 years were, on average, at a 34% […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3 June 2010 A Cochrane review found no significant difference in serious adverse events when different combinations of inhaled corticosteroids and long-acting beta2 agonists were compared in people with chronic […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 November 2010 A US exploratory study in 210 patients examined the effects of tiotropium in poorly controlled asthma. While hypothesis generating, the study does not provide grounds for clinicians […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 13 October 2010 Roflumilast▼ has been marketed as a once daily add-on treatment to bronchodilator therapy in patients with severe chronic obstructive pulmonary disease (COPD) who have frequent exacerbations. Weight […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10 September 2010 A meta-analysis has found that inhaled corticosteroids are significantly more effective than montelukast for preventing severe asthma exacerbations requiring systemic corticosteroids in schoolchildren and adolescents with mild-moderate […]

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24 June 2010 The FDA has recently rejected a New Drug Application for roflumilast (Daxas®), which was in licensing to reduce exacerbations associated with chronic obstructive pulmonary disease (COPD). Further […]