NPC Archive Item: Inhaled corticosteroids and the risk of diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 8th February 2011 A Canadian cohort study identified that patients treated for respiratory disease using inhaled corticosteroids (ICS) over a period of 5.5 years were, on average, at a 34% […]

NPC Archive Item: Comparative safety of ICS/LABA combinations in chronic asthma

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3 June 2010 A Cochrane review found no significant difference in serious adverse events when different combinations of inhaled corticosteroids and long-acting beta2 agonists were compared in people with chronic […]

NPC Archive Item: Tiotropium in asthma – still no good evidence for routine use

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 November 2010 A US exploratory study in 210 patients examined the effects of tiotropium in poorly controlled asthma. While hypothesis generating, the study does not provide grounds for clinicians […]

NPC Archive Item: Oral roflumilast▼ launched as add-on treatment for COPD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 13 October 2010 Roflumilast▼ has been marketed as a once daily add-on treatment to bronchodilator therapy in patients with severe chronic obstructive pulmonary disease (COPD) who have frequent exacerbations. Weight […]

NPC Archive Item: Inhaled corticosteroids more effective than montelukast in reducing asthma exacerbations in children

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10 September 2010 A meta-analysis has found that inhaled corticosteroids are significantly more effective than montelukast for preventing severe asthma exacerbations requiring systemic corticosteroids in schoolchildren and adolescents with mild-moderate […]

NPC Archive Item: Key licensing studies for indacaterol in COPD published

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 31 August 2010 Indacaterol▼ inhaled once daily improved trough FEV1 at 12 weeks compared to placebo in patients with moderate to severe COPD. Results from the 52-week INVOLVE study […]

NPC Archive Item: Cardiovascular safety of anticholinergics in COPD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 March 2010 A US cohort study in patients with COPD found an increased risk of CV events associated with the use of ipratropium within the past six months. […]