NPC Archive Item: As-needed inhaled corticosteroids for children with asthma — more evidence is required to change practice.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Turpeinen M, et al. Daily versus as-needed inhaled corticosteroid for mild persistent asthma (The Helsinki early intervention childhood asthma study). Arch Dis Child 2008;93:654–9 Intermittent, rather than continuous, inhaled […]

NPC Archive Item: NICE issues guidance on the prescribing of antibiotics for self-limiting respiratory tract infections

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. National Institute for Health and Clinical Excellence. Respiratory tract infections – antibiotic prescribing. Clinical Guideline 69. July 2008. Implementing NICE guidance should reduce inappropriate prescribing of antibiotics in primary […]

NPC Archive Item: Mucolytics to prevent COPD exacerbations?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Zheng J-P, Kang J, Huang S-G, et al. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): a randomised placebo-controlled study. Lancet 2008;371:2013–8 Carbocisteine reduces […]

NPC Archive Item: Revised British Asthma Guideline from SIGN and BTS

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working.      The British Asthma Guideline, produced by the British Thoracic Society and SIGN, has been updated and re-issued.  It is available as a quick reference guide as well […]

NPC Archive Item: Tiotropium – safety concern relating to possible stroke risk

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The US Food and Drug Administration (FDA) has published information about an ongoing safety review of tiotropium (Spiriva®) The manufacturer, Boehringer Ingelheim, recently informed the FDA that ongoing safety […]

NPC Archive Item: Long-acting ß2 agonists (LABAs) for asthma: review by MHRA

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The MHRA has published the findings of its review of LABAs (salmeterol and formoterol) in asthma, in the January issue of Drug Safety Update (7th January 2008). Background Concerns […]

NPC Archive Item: FDA examines safety of salmeterol in children

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. In an internal memorandum, drug safety staff at the FDA in the USA have commented that salmeterol “may have an unfavorable risk benefit ratio in the treatment of pediatric […]