NPC Archive Item: Prasugrel▼ (Efient®) in patients with STEMI

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25th March 2009 A pre-specified subgroup analysis of the TRITON-TIMI 38 trial suggests that prasugrel ▼ may be more effective than clopidogrel in those with STEMI ACS undergoing PCI. Major […]

NPC Archive Item: DH clarify guidance around new daily dose treatments for impotence.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9th March 2009 The Department of Health’s (DH) guidance on treatment for impotence (HSC1999/148) recommends in paragraph 5 that one treatment per week will be appropriate for most patients […]

NPC Archive Item: Another biologic for the treatment of psoriasis

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25th February 2009 “Subcutaneous ustekinumab▼ (Stelara®) administered every twelve weeks was more effective than placebo for the treatment of moderate to severe psoriasis. This dosing frequency appears to maintain efficacy […]

NPC Archive Item: Incretin-based therapies in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24th February 2009 Madsbad S. Treatment of type 2 diabetes with incretin-based therapies. The Lancet 2009; 373:438-39 Incretin-based therapies may offer a new option in the treatment of type […]

NPC Archive Item: Oral telcagepant, a novel treatment for acute migraine

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30th January 2009 Telcagepant 300mg improved relief of migraine pain and related symptoms two hours after a single dose as compared to placebo. The trial data suggests that the […]

NPC Archive Item: Publication bias identified for drugs receiving U.S licensing approval

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. North American authors of an observational study have found evidence of incomplete and selective publication of clinical trials that supported successful licence applications to the FDA during the time […]