NPC Archive Item: One-year follow up data for bivalirudin▼ in patients with high-risk STEMI

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 February 2010 The HORIZONS-AMI trial assessed high-risk patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). One year follow-up data to this study suggest […]

NPC Archive Item: Earlier access to new medicines

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 January 2010 Summary: A report, describing the key elements of a scheme to make available certain new medicines before they are formally licensed, has been produced by a […]

NPC Archive Item: Consultation on proposed ‘Innovation Pass’

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 December 2009 The Department of Health (DH) has launched a consultation on the Government’s proposals for an ‘Innovation Pass’ pilot. The aim of which is to make selected […]

NPC Archive Item: Darusentan as an add-on in treatment-resistant hypertension

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9 December 2009, A phase III randomised controlled trial demonstrated that darusentan reduced systolic/diastolic blood pressure by about 10/5mmHg compared with placebo in patients with treatment-resistant hypertension, but was […]

NPC Archive Item: Issues with biosimilars

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19th November 2009 An article published in the British Medical Journal has noted the high cost of newer biological drugs and offers suggestions for potential ways of making such […]

NPC Archive Item: Roflumilast in COPD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18 November 2009, Two one-year RCTs (AURA and HERMES) showed that roflumilast modestly improved lung function in patients with severe COPD who were symptomatic and not using an inhaled […]

NPC Archive Item: Ticagrelor — another antiplatelet for ACS

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 December 2009 Ticagrelor plus aspirin was significantly more effective than clopidogrel plus aspirin in preventing vascular events in patients with acute coronary syndrome in the PLATO trial (NNT=53). […]