NPC Archive Item: Roflumilast in COPD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 18 November 2009, Two one-year RCTs (AURA and HERMES) showed that roflumilast modestly improved lung function in patients with severe COPD who were symptomatic and not using an inhaled […]

NPC Archive Item: Ticagrelor — another antiplatelet for ACS

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 December 2009 Ticagrelor plus aspirin was significantly more effective than clopidogrel plus aspirin in preventing vascular events in patients with acute coronary syndrome in the PLATO trial (NNT=53). […]

NPC Archive Item: Denosumab for postmenopausal osteoporosis

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 September 2009 In the FREEDOM study, subcutaneous denosumab was compared with placebo given at 6 monthly intervals over 36 months to almost 8,000 women with postmenopausal osteoporosis. While […]

NPC Archive Item: Latest data on saxagliptin

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th July 2009, A phase III, 24 week randomised controlled trial has assessed the efficacy and short-term safety of saxagliptin 2.5, 5 and 10mg versus placebo as add-on therapy […]

NPC Archive Item: Is clopidogrel ACTIVE for atrial fibrillation?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 17th April 2009 Clopidogrel plus aspirin reduced the risk of a vascular composite end point compared with aspirin alone in people with AF who were at increased risk of […]

NPC Archive Item: Update on new treatments for chronic idiopathic thrombocytopenic purpura

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 6th April 2009 Romiplostim▼ has recently been licensed for idiopathic thrombocytopenic purpura (ITP), and a new study of oral eltrombopag (not currently licensed in Europe) showed increased blood platelet […]