NPC Archive Item: Denosumab for postmenopausal osteoporosis

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 September 2009 In the FREEDOM study, subcutaneous denosumab was compared with placebo given at 6 monthly intervals over 36 months to almost 8,000 women with postmenopausal osteoporosis. While […]

NPC Archive Item: Latest data on saxagliptin

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th July 2009, A phase III, 24 week randomised controlled trial has assessed the efficacy and short-term safety of saxagliptin 2.5, 5 and 10mg versus placebo as add-on therapy […]

NPC Archive Item: Is clopidogrel ACTIVE for atrial fibrillation?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 17th April 2009 Clopidogrel plus aspirin reduced the risk of a vascular composite end point compared with aspirin alone in people with AF who were at increased risk of […]

NPC Archive Item: Update on new treatments for chronic idiopathic thrombocytopenic purpura

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 6th April 2009 Romiplostim▼ has recently been licensed for idiopathic thrombocytopenic purpura (ITP), and a new study of oral eltrombopag (not currently licensed in Europe) showed increased blood platelet […]

NPC Archive Item: Prasugrel▼ (Efient®) in patients with STEMI

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25th March 2009 A pre-specified subgroup analysis of the TRITON-TIMI 38 trial suggests that prasugrel ▼ may be more effective than clopidogrel in those with STEMI ACS undergoing PCI. Major […]

NPC Archive Item: DH clarify guidance around new daily dose treatments for impotence.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9th March 2009 The Department of Health’s (DH) guidance on treatment for impotence (HSC1999/148) recommends in paragraph 5 that one treatment per week will be appropriate for most patients […]