NPC Archive Item: February Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 4th February 2009 The MHRA and CHM have published the February edition of Drug Safety Update. This issue gives […]

NPC Archive Item: Selenium, vitamin E or vitamin C do not prevent prostate cancer

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Two large, double-blind, placebo-controlled randomised trials fail to demonstrate a benefit of selenium, vitamin E or vitamin C in preventing prostate cancer. Action: Clinicians should not recommend the use […]

NPC Archive Item: December Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 11th December 2008 The MHRA and CHM have published the December edition of Drug Safety Update. This issue gives […]

NPC Archive Item: November Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 12th November 2008 The MHRA and CHM have published the November edition of Drug Safety Update. This issue highlights […]

NPC Archive Item: Early days for alemtuzumab▼ in early MS

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The CAMMS223 Trial Investigators. Alemtuzumab▼ vs. Interferon Beta-1a in Early Multiple Sclerosis. N Engl J Med 2008; 359:1786-801 Compared with interferon beta-1a, alemtuzumab▼ reduced the annualised risk of relapse and sustained […]

NPC Archive Item: October Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 9th October 2008 The MHRA and CHM have published the October edition of Drug Safety Update. Included in this […]

NPC Archive Item: FDA safety warning on risk of serious fungal infections with TNF-α inhibitors

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. FDA advises that the manufacturers of the tumour necrosis factor alpha (TNF-α) inhibitors, adalimumab▼, etanercept▼, infliximab▼, and certolizumab* must strengthen existing warnings to highlight the risk of potentially fatal […]

NPC Archive Item: Seeding trials – marketing framed as science

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Hill KP et al.  The ADVANTAGE seeding trial: a review of internal documents.  Ann Intern Med 2008; 149: 251-258 Evidence suggests that some clinical trials may have more to […]