NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Lipscombe L, Gomes T, Lévesque LE, et al. Thiazolidinediones and cardiovascular outcomes in older patients with diabetes. JAMA. 2007;298:2634-43. A large population-based study from Canada increases concerns over the […]
Category Archives: Cardiovascular disease
NPC Archive Item: Ezetimibe▼ in hypercholesterolaemia: NICE guidance
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. What is this about? NICE has published a technology appraisal covering ezetimibe▼ in hypercholesterolaemia. What do NICE say? NICE guidance relates only primary (heterozygous-familial or non-familial) hypercholesterolaemia, and not […]
NPC Archive Item: Awareness, agreement, adoption and adherence to hypertension guideline recommendations
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Heneghan C, et al. Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherence. BJGP 2007;57:948–52 What is the background to this? This study aimed to understand GPs’ […]
NPC Archive Item: Current volume of angiotensin receptor blockers (ARBs) prescribing is not justified by the evidence
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Matchar DB, McCrory DC, Orlando LA, et al. Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) for Treating Essential Hypertension. Comparative Effectiveness Review No. […]
NPC Archive Item: Fibrates not first choice drugs for most patients, say MHRA and CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Fibrates should not be used as first line lipid-lowering drugs for primary or secondary prevention of cardiovascular disease. So say the MHRA and CHM in the most recent issue […]
NPC Archive Item: Treat TIAs and minor strokes urgently
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Rothwell PM et al. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet Neurology Published […]
NPC Archive Item: Warfarin more effective than aspirin for stroke risk in AF but what about the risk of bleeding? – The BAFTA study
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial What […]
NPC Archive Item: Lowering blood pressure saves lives in people with type 2 diabetes – the ADVANCE study.
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. What does this study claim? The Lancet published the results of the ADVANCE study on the 2nd September 2007. It examined the effect of a fixed combination of an […]
NPC Archive Item: ASPEN study: atorvastatin ineffective in reducing CVD outcomes in type 2 diabetes
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. You may have missed the results of the ASPEN study when it was published last year, as it did not seem to hit the headlines. Could it have something […]
NPC Archive Item: Is Switching From Atorvastatin To Simvastatin Harmful?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Times (6th September 2007) has reported a poster from the European Society of Cardiology Congress. The poster itself is available from the Wall Street Journal website. The headline […]