NPC Archive Item: NPC Podcast – 29 March 2012

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Join the NPC evidence-based therapeutics team as they discuss some important recent studies and therapeutic news. This month: Review aliskiren prescribing Proton pump inhibitors (PPIs) and risk of hip […]

NPC Archive Item: Pioglitazone▼ and the occurrence of bladder cancer

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24 June 2011 The European Medicines Agency (EMA) has published an update on their ongoing benefit-risk review of pioglitazone▼–containing medicines and the occurrence of bladder cancer. The Committee for […]

NPC Archive Item: New meta-analysis on intensive statin therapy supports NICE guidance

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4 May 2011 A large meta-analysis (>40,000 patients) of randomised controlled trials did not find a statistically significant reduction in all-cause or cardiovascular (CV) mortality with intensive statin therapy, […]

NPC Archive Item: Meta-analysis supports SSRIs as initial drug treatment for anxiety

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4th May 2011 This meta-analysis of 27 randomised controlled trials (RCTs) of nine drug treatments for generalised anxiety disorder (GAD) ranked sertraline first for tolerability and fluoxetine first for […]

NPC Archive Item: Zinc for prevention and treatment of the common cold

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4 May 2011 A Cochrane review concluded that oral zinc may have benefits for prevention and treatment of the common cold. However, these benefits are uncertain because of marked […]

NPC Archive Item: CONTROL blood glucose in type 2 diabetes — but individualise care

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 6th April 2011 The CONTROL meta-analysis of four large RCTs found that more-intensive blood glucose lowering reduced the absolute risk of major cardiovascular (CV) events by 0.9% over 4.4 […]

NPC Archive Item: Estimating lifetime cardiovascular risk – we can, but should we?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9th March 2011 This large UK cohort study used data collected from general practice databases to develop and validate a new QRISK cardiovascular risk assessment tool to estimate lifetime […]